Johnson & Johnson vaccine is not the only vaccine whose administration has been suspended in some parts of the world, because some countries have also stopped using AstraZeneca serum
United States It is recommended to suspend use this Tuesday vaccine Oppose covid-19 de Johnson & Johnson (J&J), a serum similar to traditional medicine, just like AstraZeneca, the technology used is Pfizer and Moderna.
The suspension came after the U.S. health department detected six adverse cases among six vaccinated women between 18 and 48 years old. One of them died and the other was severe. They had developed a rare type before. Cerebral thrombosis.
So far, the United States has granted emergency use permits for anti-HIV preparations. Collaborators from Pfizer and Moderna, Two doses are required, while Johnson & Johnson is a single dose, and AstraZeneca has not yet applied for permission.
Johnson & Johnson vaccine is not the only vaccine in the world whose administration has been suspended, because some countries/regions have also stopped using it AstraZeneca After finding a case of thrombosis.
Johnson & Johnson is like a traditional vaccine, which is easier to distribute and store than a vaccine based on Vigor Messenger RNA Like Pfizer and Moderna.
This is because Johnson & Johnson, like AstraZeneca, uses a technology that scientists have been studying for decades: a technology called Adenovirus.
Adenovirus is a common virus that can cause diseases such as colds or flu.
The Johnson & Johnson vaccine uses an inactivated adenovirus that sends instructions to the vaccinated person’s body to fight COVID-19. The virus has nothing to do with the coronavirus and cannot replicate or cause viral infections among vaccinators.
virus SARS-CoV-2, The proteins that cause covid-19 have proteins that enter the cell: these substances are called spinous proteins because of their shape, and are the target of vaccines and treatments for the disease.
vaccine Johnson Accept the genetic instructions of the virus to construct the spike protein, but with the preparation Pfizer and Moderna, These genetic data are stored in single-stranded RNA (ie, single-stranded), and the serum uses double-stranded (double-stranded) DNA.
What Johnson & Johnson researchers did was to add the protein’s gene to the end of the protein. coronavirus Modified adenovirus so that it enters the cell without replicating within the disease or developing in the disease.
Scientists have been studying vaccines based on adenovirus for decades.
In fact, Johnson & Johnson has developed an adenovirus-based Ebola vaccine and is conducting experiments to obtain serum against diseases such as Zika and AIDS.
Adenovirus vaccine ratio Messenger RNA Because DNA is not that fragile, and the protein layer covering this inactivated virus helps protect the genetic material inside.
In this way, the J&J preparation work can be stored in cold Up to three months at a temperature between 36 to 45 degrees Fahrenheit (2 to 8 degrees Celsius), which is different from the extremely low storage temperature required by Moderna and Pfizer.