The P1 variant of the coronavirus is more contagious, although no studies have concluded that it is more lethal
This Brazil variant A type of coronavirus called P1 is little known, but it has aroused the alarm of the world because it is More contagiousMany countries have suspended the flights of the South American giant, the epicenter of the epidemic.
P1 appeared in Manaus, the capital of Amazonas state, in December last year, but was not confirmed as a new variant until January. JapanSome of them are travelers returning from that area in northern Brazil.
In some countries in South America, such as Argentina, Chile, Uruguay, Bolivia, Peru and Venezuela, this variant has also been detected. It also reached the United States, Canada, Germany and France. On Monday, the United States announced that it had suspended flights to Brazil like other countries.
Like the South African variant, P1 also has mutations E484K, qAccording to some studies, it may cause more infections than other strains because it requires more antiviral antibodies.
It also has many variations in Spike protein. Through these variations, virus Enter the cells to infect them.
“From an epidemiological point of view, this variant will destabilize unstable areas where the spread of the virus is almost impossible to control, and the infrastructure is very small, which leads to hospital closures. The patient died Due to hypoxia.
He added that the Brazilian government even “should close the border to prevent this variant from entering other countries, such as poorer countries such as Peru.”
So far, no research has concluded that P1 is More deadly.
In a preliminary investigation, Orellana found that compared with Manila, P1 did not increase the mortality rate in Manaus Hospital. The first wave of pandemic, April 2020.
The analysis is consistent with two studies published on Tuesday that the UK mutation does not cause More severe cases of covid-19.
In recent weeks, the increase in the number of deaths from covid-19 in Brazil is due to hospital closures, “because this mutation is more contagious and is also due to the general relaxation of the population facing preventive measures” and the adoption of quarantine measures,” Orellana added Say.
Preliminary research shows China CoronaVac vaccine, It is the most used drug in Brazil and is effective against P1 as well as Pfizer and AstraZeneca.
P1 variants are found almost all over the Brazilian territory, although there is a lack of data to measure the percentage of infections in each region.
The uncontrolled spread of the virus resulted in New mutations, Variants with the same strain, such as P2 circulating in Rio de Janeiro or P4 recently discovered in the neighboring Belo Horizonte state of Minas Gerais.
In order to avoid the spread of these mutations, “ideally, like England or Israel, there are enough doses for mass vaccination and lock-in at the same time,” adds Pasternak, a microbiologist.